2D transition metal sulfide “canvas” for biomolecule capture and sensing

November 14, 2022,Liu Bilu/Lei Yu research group of Shenzhen International Graduate School of Tsinghua UniversityatNano Research EnergyPublished a review article titled “Biomolecule Capturing and Sensing on 2D Transition Metal Chalcogenide Canvas”.

Figure 1: Schematic representation of the properties and applications of 2D TMD in biomolecule capture and sensing.

In recent years, scientists have been working on the prevention, diagnosis and treatment of diseases. Especially during the new crown pneumonia epidemic, it is possible to carry out biomolecules with high confidenceIn vitro and in vivo testingIt is essential for disease prevention and diagnosis. Modern human life is generally under great stress, and ubiquitous stress can lead to abnormalities in hormones such as dopamine, cortisol and adrenaline.Noninvasive monitoring of body fluidsThese biomarkers (e.g., sweat, tears and saliva) can help in rapid and accurate stress assessment, mental illness diagnosis, and awareness of their physical and mental health. Therefore, biosensors are inHealth diagnosis, environmental monitoring, forensic industryetc. have a very wide range of applications.

Since the successful preparation of graphene in 2004, two-dimensional (2D) materials such as transition metal sulfides (TMDs) have been due to their uniquenessVan der Waals structure and easy to regulate at the atomic scaleand other properties have aroused the interest of many researchers. In recent years, due to itsLarge surface area and high surface sensitivity, as well as its uniqueElectrical, optical and electrochemical propertiesTMD has a wide range of applications in biomedical fields and other fields. In this review, the authors focus on the latest methods for regulating the properties of 2D TMDs and their findingsApplications in the field of biosensing; Special provision is providedDefect engineering and morphological controlto design and modulate 2D TMDs to achieve their multiple functions for molecular capture and sensing. Moreover, the author is right2D TMD-based biosensors are compared to conventional sensing systems, deepening the reader’s understanding of its mechanism of action. Finally, the authors point out the opportunities and challenges encountered by 2D TMDs in this emerging field.

Related paper information:

Y. Bai, L. Sun, Q. Yu, et al. Biomolecule capturing and sensing on 2D transition metal dichalcogenide canvas. Nano Research Energy.


Nano Research Energyis a companion journal of Nano Research, (ISSN: 2791-0091; e-ISSN: 2790-8119; Official Website: in March 2022, Professor Qu Liangti of Tsinghua University and Professor Chunyi Zhi of City University of Hong Kong serve as editors-in-chief.Nano Research EnergyIt is an international multidisciplinary and English-based open access journal, focusing on the cutting-edge research and application of nanomaterials and nanoscience and technology in new energy-related fields, benchmarking against top international energy journals, and committed to publishing high-level original research and review papers, which has been selected2022 China Science and Technology Journals Excellence Action Plan – High Starting Point New Journal Project。 APC fees will be waived until 2023, and teachers are welcome to submit their papers. To submit, please contact:

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