Research on the anti-streptococcal infection of gemfibroapia has progressed

Outbreaks of streptococcal disease during the hot season have caused huge losses to the tilapia industry. Therefore, finding an effective feed additive is beneficial to reduce the occurrence of streptococcal disease in high temperature season, which is of great significance to further improve the efficiency of tilapia farming.

Recently, the team of Ren Mingchun, a freshwater fishery research center of the Chinese Academy of Fishery Sciences and a scientist at the nutritional demand and feed post of freshwater bass in the national characteristic freshwater fish industry technology system, has made new progress in the research of geifulapia against streptococcal infection. The related research paper was published in Antioxidants.

Previous studies have proved that eucommia eucommia leaf extract (ELE) as a feed additive has no drug resistance, no toxic side effects, and is rich in bioactive compounds (such as flavonoids, chlorogenic acids, polysaccharides), which has anti-inflammatory, antioxidant, antiviral and liver protection effects. Therefore, the team used eucommia eucommia leaf extract to study the antioxidant capacity, immune function and high-temperature antibacterial ability of gemfulofia. It was found that ELE supplementation in feed would not affect the growth performance of geflotilla, and when the amount of ELE supplementation was 0.04%~0.06%, it could promote intestinal antioxidant capacity by activating the Nrf2 signaling pathway, inhibit the TLR2-MyD88-NF-κB signaling pathway, enhance the immune response, and ultimately improve the disease resistance of GIFT to Streptococcus agalactiae.

Image source: Freshwater Fisheries Research Center, Chinese Academy of Fishery Sciences

The research work was supported by the National Key R&D Program and the related projects of the characteristic freshwater fish industry technology system. (Source: Zhang Qingdan, China Science News)

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